Endocrine Abstracts

Antithyroid drugs frequently used in management of hyperthyroidism may lead to liver damage. Hepatotoxicity is a rare but potentially fatal complication. The aim of this study was to present two cases of severe liver damage and the role of 131-I treatment in such cases.Case 1: A women 49 years of age with Graves hyperthyroidism was treated with metimazol (30 mg next 10 mg). After 1 month the utricarial skin rush was observed and the drug was changed to P...

Introduction: Intravenous methylprednisolon pulses (IVMP) are commonly accepted treatment in Graves orbitopathy (GO) However acute and severe liver damage has been reported in sporadic cases during such therapy. The aim of this study was to present the cases of severe liver damage after second and third course of IVMP.Case report: The white women 60 years of age with Graves disease diagnosed in 1983. Firstly she was treated with antythyroid drugs for 2 y...